目的:探讨晚期肺癌合并支气管内肿瘤患者在化疗基础上联合光动力治疗的近期临床效果。方法:选取临床病理明确诊断晚期肺癌患者4例,男性,平均年龄65.8岁。其中腺癌2例,鳞癌2例。4例患者在完成4次化疗后,其中1例是手术1年后复发,支气管内肿瘤阻塞管腔,经冷冻和氩气刀治疗后。采用进口光敏剂Photofrin,患者在暗室内静脉注射,48~50 h后给予经电子支气管 Objective: To investigate the short-term clinical effect of combined photodynamic therapy based on chemotherapy in advanced lung cancer with intrabronchial tumor. Methods: Four cases of advanced lung cancer were diagnosed clinically and pathologically, with a mean age of 65.8 years. Of which 2 cases of adenocarcinoma, squamous cell carcinoma in 2 cases. Of the four patients who completed four cycles of chemotherapy, one of them recurred after one year of surgery, the intrabronchial tumor blocked the lumen, and was frozen and treated with an argon knife. The use of imported photosensitizer Photofrin, patients intravenous injection in the dark room, after 48 ~ 50 h given by the electronic bronchus