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【目的】探讨正常胰腺和胰腺癌的MR动态增强扫描特征及探讨其对胰腺癌诊断的临床应用价值。【方法】87例患者行MR动态增强扫描,其中正常胰腺74例,胰腺癌13例,采用3D/WATS/FFE序列结合SENSE技术行动态增强扫描,在开始注射对比剂后0s、25s、35s、60s、90s和2min扫描。测量并比较正常胰腺和胰腺癌在0s、25s、35s、60s、90s及2min各时相的信噪比(SNR)、信号强度比(SIR),比较各时相肿瘤组织与瘤周正常组织的SNR、强化百分比。【结果】正常胰腺35s强化达到峰值。胰腺癌呈渐进性强化,90s强化达到峰值,在0s、25s、35s时相肿瘤病灶平均信号强度均低于正常胰腺,25s、35s的图像上,两者之间信号差值最大,90s两者之间信号值接近。【结论】MR动态增强扫描在动脉期及胰腺期肿瘤组织与瘤周正常组织SNR最明显。MR动态增强扫描对胰腺癌诊断有一定的临床价值。
【Objective】 To investigate the dynamic contrast-enhanced MR features of normal pancreas and pancreatic cancer and to explore its clinical value in the diagnosis of pancreatic cancer. 【Methods】 87 patients underwent dynamic contrast-enhanced MR scanning. There were 74 cases of normal pancreas and 13 cases of pancreatic adenocarcinoma. Dynamic 3D-WATS / FFE combined with SENSE technique was used to detect dynamic contrast-enhanced scanning. After 0s, 25s, 35s, 60s, 90s and 2min scans. The signal to noise ratio (SNR) and signal intensity ratio (SIR) of normal pancreas and pancreatic cancer at 0, 25, 35, 60, 90 and 2 minutes were measured and compared. SNR, percent enhancement. 【Results】 The normal pancreas peaked at 35s. The pancreatic adenocarcinoma showed progressive enhancement and peaked at 90s. The average signal intensity of tumor lesions at 0s, 25s and 35s was lower than that of normal pancreas, 25s and 35s, and the difference between the two signals was the largest. Close to the signal value. 【Conclusions】 The SNR of dynamic contrast-enhanced MR imaging in the arterial phase and pancreatic phase is the most obvious among the tumor tissues and normal tissues. MR dynamic enhanced scan for the diagnosis of pancreatic cancer has some clinical value.