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近年来，变应性疾病的发病率逐年上升，常见的变应性疾病包括变应性鼻炎、变应性哮喘和湿疹，其临床症状严重影响患者的生活质量，甚至危及患者生命（如重症哮喘）。多项研究已证实，空气污染物及饮食结构与变应性疾病密切相关，其潜在的发病机制成为研究热点。综述几种主要室内环境污染物以及饮食结构对变应性疾病的影响，并对其可能的发病机制进行阐述。“,”Recently,the prevalence of allergic disease increased rapidly.Common allergic diseases mainly include aller-gic rhinitis ,allergic asthma and eczema.Clinical symptoms seriously affect the patients’quality of life.Currently, some studies have defined the relation between indoor air pollutants and allergic diseases as well as that between diet and allergic diseases.The potential pathogenesis has become hotspot in recent years.This paper reviews the impact of sever-al main indoor air pollutants and diet to allergic diseases.Potential mechanism also be elaborated in this review.