黄体生成激素稀放激素(LRH)主要是下丘脑弓状核合成,贮存于正中隆起或特殊的脑室细胞中,在高级中枢系统的神经介质及性甾体激素的刺激下进入垂体门脉系统,引起垂体LH及FSH的释放。自从1971年Schally从下丘脑分离、提纯并阐明其化学结构以来,对LRH结构与功能的研究越来越深入,目前已合成了各种类型的类似物,有的效能超过天然的数百倍。 Luteinizing hormone-producing hormone (LRH) is mainly hypothalamic arcuate nucleus synthesis, stored in the median bulge or special ventricular cells, the central nervous system in the central nervous system and steroid hormone into the pituitary portal system, Caused by the release of pituitary LH and FSH. Since 1971, when Schally isolated, purified and elucidated its chemical structure from the hypothalamus, studies on the structure and function of LRH have become more and more in-depth. Various types of analogs have been synthesized and their efficacy is several hundred times more than that of natural ones.