全血谷胱甘肽还原酶活性系数评价实验性核黄素缺乏的研究

来源 :中国人民解放军军事医学科学院院刊 | 被引量 : 0次 | 上传用户:renyuh
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通过大白鼠的实验性核黄素缺乏和补充,证明全血谷胱甘肽还原酶(BGR)的活性系数(AC)能反映机体的核黄素营养状况。动物缺乏核黄素一周后,AC值即迅速增高,而补充核黄素后又恢复正常。AC值与全日尿中核黄素排出量比较,缺乏时变化得早,故用来评定核黄素缺乏较为灵敏。AC值的测定方法经改进后,全血用量可减至0.02毫升,并省去了一些特殊装置,为现场调查时提供了方便。 Through experimental riboflavin deficiency and supplementation in rats, it has been demonstrated that the activity coefficient (AC) of whole blood glutathione reductase (BGR) reflects the body’s riboflavin nutritional status. One week after animals lacked riboflavin, the AC value increased rapidly and returned to normal after supplementation with riboflavin. AC value and full-day urinary riboflavin compared to lack of early change, it is used to assess the lack of riboflavin more sensitive. After the method of determination of AC value is improved, the amount of whole blood can be reduced to 0.02 ml, and some special devices are omitted, which provides convenience for field investigation.
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