大剂量维生素B_(12)注射治疗三叉神经痛有一定疗效,现将动物试验及100例的治疗观察结果报导于下: 动物试验 用家兔9只,体重2～3公斤,于戊巴比妥钠静脉加局部麻醉下,手术暴露一侧坐骨神经,用皮内注射针刺透神经外膜,进入神经干内,在3只兔注入维生素B_(12)0.8ml(400μg),另3只兔注入长效维生素B_(12)0.8ml(200μg),其余3只兔注入生理盐水0.8ml作对照(并在3号兔之另侧坐骨神经注射维生素B_(12)0.8ml)。拔针后于药物扩散至神经的上下端各夹银夹1个作标记。注完后神经干上出现点及 High doses of vitamin B_ (12) injection of trigeminal neuralgia have a certain effect, now the animal test and 100 cases of therapeutic observations reported in the next: animal rabbits, weighing 2 to 3 kg in pentobarbital Under the sodium vein plus local anesthesia, one side of the sciatic nerve was surgically exposed, and the epineurium was penetrated by the intradermal injection needle into the nerve trunk. In 3 rabbits, 0.8 ml (400 μg) of vitamin B 12 was injected and 3 rabbits 0.8 ml (200 μg) of long-acting vitamin B_ (12) and 0.8 ml of normal saline were injected into the other three rabbits (and 0.8 ml of vitamin B_ (12) was injected into the other sciatic nerve of rabbit No. 3). Pull the needle after the drugs spread to the upper and lower ends of each clip silver clip 1 for the mark. Note after the nerve stem points and