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川芎嗪是心、脑血管疾病防治中的有效药物。资料表明 ,川芎嗪具有改善疾病状态下的内皮细胞的功能[1] 。但川芎嗪对血管内皮细胞合成和分泌一氧化氮(ＮｉｔｒｉｃＯｘｉｄｅ ,ＮＯ) ,组织因子 (ＴｉｓｓｎｅＦａｃｆｏｒＴＦ)及组织因子途径抑制物 (ＴｉｓｓｕｅＦａｃｔｏｒＰ
Ligustrazine is an effective drug in the prevention and treatment of heart and cerebrovascular diseases. The data show that ligustrazine has the function of improving endothelial cells under disease conditions [1]. However, tetramethylpyrazine synthesizes and secretes nitric oxide (NO), tissue factor (TissneFacforTF) and tissue factor pathway inhibitor (TissueFactorP) on vascular endothelial cells.