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目的分析早发型重度子痫前期期待治疗时限及妊娠结局。方法选择无严重并发症早发型重度子痫前期病人66例,以其终止妊娠前孕周分为3组,A组发病孕周<28周(10例),B组发病孕周为28~31+6周(24例),C组发病孕周32~33+6周(32例)。分析3组孕期治疗时限、孕妇并发症、胎儿及围生儿结局。结果 3组孕妇并发症发生率随着孕周的延长有升高的趋势,但差异无显著性(P>0.05)。胎儿窘迫、胎死宫内、新生儿窒息及新生儿死亡的发生率随孕周增长而下降,差异有显著性(P=0.000~0.006)。B组的期待治疗时间明显较A、C组长(F=7.572,q=7.587、6.457,P<0.05),而A组和C组比较差异无显著性(P>0.05)。3组剖宫产率比较差异无显著性(P>0.05)。结论早发型重度子痫前期非手术治疗可行,但在治疗中应严密监测,权衡利弊,适时终止妊娠,剖宫产仍是终止重度子痫前期的主要治疗方法。
Objective To analyze the expected treatment duration and pregnancy outcome of early-onset severe preeclampsia. Methods Sixty-six patients with severe preeclampsia without severe complications were enrolled in this study. Pregnancy was divided into three groups before gestation. The gestational age of group A was less than 28 weeks (n = 10), and that of group B was 28 to 31 +6 weeks (24 cases), C group onset of gestational weeks 32 ~ 33 +6 weeks (32 cases). Analysis of three groups of treatment duration, complications of pregnancy, fetal and perinatal outcomes. Results The incidence of complications of pregnant women in the three groups tended to increase with the prolongation of gestational age, but the difference was not significant (P> 0.05). The incidence of fetal distress, intrauterine fetal death, neonatal asphyxia and neonatal death decreased with gestational age, the difference was significant (P = 0.000 ~ 0.006). The expectant treatment time in group B was significantly longer than that in group A and C (F = 7.572, q = 7.587, 6.457, P <0.05), but there was no significant difference between group A and C (P> 0.05). There was no significant difference in cesarean section rate between the three groups (P> 0.05). Conclusion Non-surgical treatment of early-onset severe preeclampsia is feasible, but should be closely monitored in the treatment, weighing the pros and cons, timely termination of pregnancy, cesarean section is still the main treatment to terminate severe preeclampsia.