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目的研究冠脉造影数字跟踪技术测定冠脉血流速度与Doppler血流速度之间的相关性。方法入选住院冠脉造影病人40例,包括左前降支(LAD)单支病变行介入治疗(PCI)10例,诊断性冠脉造影30例(冠脉造影正常、心肌桥、轻-中度狭窄病变)。所有病例采用冠脉造影数字跟踪技术测定LAD平均血流速度(CFVm),其中15例用冠脉造影TIMI计帧法测定LAD血流速度(帧.f)。另15例使用Doppler导丝测定LAD平均峰值血流速度(APV),并与CFVm作相关分析。结果冠脉造影数字跟踪法测定LAD的CFVm(18.58±6.46)与Doppler导丝测得的LAD近端(17.42±5.99)和远端(17.93±5.78)的APV显著相关(r=0.79.r=0.64);而与TIMI计帧法血流速度呈弱相关(r=-0.47)。PCI治疗成功后,随着狭窄最小腔径增加,跟踪法血流速度加快(P<0.01),CFVm≥20cm/s。结论冠脉造影数字跟踪技术测定冠脉血流速度与Doppler血流速度显著相关,两者表达单位一致,方法简便易行,重复性好,可以用作常规冠脉造影血流速度定量指标。
Objective To study the correlation between coronary blood flow velocity and Doppler blood flow velocity by coronary angiography digital tracking technique. Methods Forty patients undergoing coronary angiography were enrolled, including 10 cases of single coronary artery disease (PCI), 10 cases of coronary angiography (coronary angiography, myocardial bridge, mild to moderate stenosis Lesions). All patients underwent coronary angiography with digital tracking for mean LAD velocity (CFVm), of which 15 were measured by coronary angiography with TIMI frame rate for LAD (frame .f). In the other 15 cases, the mean peak blood flow velocity (APV) of LAD was measured by Doppler guidewire and correlated with CFVm. Results Coronary angiography digital tracking showed significant correlations between CFVm of LAD (18.58 ± 6.46) and APV of proximal LAD (17.42 ± 5.99) and distal (17.93 ± 5.78) measured by Doppler guidewire (r = 0.79, r = 0.64). However, it was weakly correlated with TIMI flow rate (r = -0.47). After successful PCI, with the increase of the minimum stenosis diameter, the blood flow velocity of the follow-up method was accelerated (P <0.01), CFVm≥20cm / s. Conclusions Coronary artery blood flow velocity is significantly correlated with Doppler blood flow velocity by coronary angiography digital tracking technique. The expression units are consistent. The method is simple, reproducible and can be used as a quantitative indicator of blood flow velocity in conventional coronary angiography.