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目的:探讨高血压脑出血患者采用加味温胆汤治疗对患者康复及后遗症的影响。方法:采用随机数字表法将省中医院神经一科2005年5月~2007年8月收治的120例脑出血后遗症患者分为研究组和对照组各60例,对照组采用西医常规治疗,研究组在对照组的基础上加用中药汤剂温胆汤进行治疗,比较两组患者治疗前与治疗后第8周的神经功能缺损评分(NHISS)、日常生活能力评分(ADL)、运动能力评分(Fugl-Meyer)、血脂指标及临床症状改善情况。结果:治疗前后研究组和对照组患者的TC、TG、HDL-C、LDL-C差异不显著(P>0.05);治疗后两组的TC、TG、HDL-C、LDL-C较治疗前均显著好转(P<0.05)。治疗前研究组和对照组的NIHSS、ADL、运动能力评分差异均不显著(P>0.05);治疗后,研究组的NIHSS评分显著低于对照组,ADL、运动能力评分显著高于对照组(P<0.05)。治疗8周后,研究组的疗效分布显著优于对照组(P<0.05),研究组的总有效率78.33%显著高于对照组的58.33%(P<0.05)。结论:对高血压脑出血患者采用加味温胆汤治疗对患者康复具有积极效果,能够有效的改善患者的神经功能、日常生活能力及活动能力,降低后遗症的病残作用。
Objective: To investigate the effect of Modified Wendan Decoction on rehabilitation and sequelae of patients with hypertensive intracerebral hemorrhage. Methods: A total of 120 patients with cerebral hemorrhage sequelae who were admitted to Department of Neurology, Provincial Hospital of Traditional Chinese Medicine from May 2005 to August 2007 were divided into study group (60 cases) and control group (60 cases) respectively. The control group was treated with conventional western medicine The rats in the control group were treated with decoction of decoction of Wen Wei Dan, and the scores of NHISS, ADL, exercise capacity score of the two groups before and after treatment were compared (Fugl-Meyer), blood lipid indicators and clinical symptoms improved. Results: TC, TG, HDL-C and LDL-C in study group and control group before and after treatment showed no significant difference (P> 0.05). After treatment, TC, TG, HDL-C and LDL- Were significantly improved (P <0.05). There was no significant difference in NIHSS, ADL and exercise capacity scores between the two groups before treatment (P> 0.05). After treatment, the NIHSS score of the study group was significantly lower than that of the control group, ADL and exercise capacity score was significantly higher than that of the control group P <0.05). After 8 weeks of treatment, the efficacy of the study group was significantly better than that of the control group (P <0.05). The total effective rate of the study group was 78.33%, significantly higher than that of the control group (58.33%, P <0.05). Conclusion: The treatment of hypertensive intracerebral hemorrhage with Jiaweweantan Decoction has positive effect on the rehabilitation of patients, which can effectively improve the patients’ neurological function, daily living ability and activity ability, and reduce the morbidity and mortality of sequelae.