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目的了解株洲市AFP监测系统运行状况。方法利用中国免疫规划监测信息管理系统(3.0.0.5版)数据库及SPSS13.0软件进行整理,对株洲市2007-2009年AFP病例个案调查表、随访表和实验室病毒学监测数据进行分析。结果 1、株洲市三年时间共报告AFP病例62例,各年度AFP病例报告发病率均达2/10万以上,所有病例均为脊灰排除病例。2、服苗情况:未完成OPV基础免疫、免疫史不详和免疫空白的病例分别占6.45%、4.84%和1.61%。3、三年中AFP病例从调查、采样、随访各项年度指标均达国家要求。4、流行病学特征:62例AFP各月均有病例发生,无明显季节性;报告来自全市8个县区,但各县、区AFP监测工作不平衡;年龄分布主要集中在1～6岁年龄组,占95.16%。男女比例为2.26:1。5、实验室结果 :脊灰Ⅱ型病毒阳性2例,阳性率为3.23%,其它肠道病毒(EV)10例,占16.13%。6、60～75d随访59例恢复正常,3例仍残留麻痹,占4.84%。结论株洲市多年未发现本土脊灰野病毒引起的麻痹病例,继续保持无脊灰状态,AFP监测系统运行敏感度、及时性均达到WHO规定的标准。AFP病例监测与脊髓灰质炎疫苗免疫工作亟待加强。
Objective To understand the operation status of AFP monitoring system in Zhuzhou City. Methods The data of China Immunization Surveillance Information Management System (version 3.0.0.5) and SPSS13.0 were used to analyze the case-based questionnaire, follow-up table and laboratory virological monitoring data of AFP cases in Zhuzhou City from 2007 to 2009. Results 1, A total of 62 cases of AFP were reported in Zhuzhou City in three years. The incidence of AFP cases in each year reached more than 2 / 100,000, all cases were polio-negative cases. 2, the situation of service: incomplete OPV basic immunization, unknown history of immunization and immune blank cases accounted for 6.45%, 4.84% and 1.61%. 3, Three years of AFP cases from the survey, sampling, follow-up of the annual indicators reached the national requirements. Epidemiological characteristics: 62 cases of AFP cases occur each month, no obvious seasonal; reports from the city’s eight counties, but counties, districts AFP monitoring work is uneven; the age distribution mainly concentrated in 1 to 6 years old Age group, accounting for 95.16%. The male-female ratio was 2.26: 1.5. Laboratory results: 2 were positive for poliovirus type 2, the positive rate was 3.23%. Other enterovirus (EV) was 10 (16.13%). Sixty-nine follow-up of 60 to 75 days returned to normal, 3 cases remained paralysis, accounting for 4.84%. Conclusion Zhuzhou City has not found any paralysis cases caused by poliovirus in mainland for many years and continues to maintain the status of polio-free state. The sensitivity and timeliness of AFP monitoring system have reached the standards set by WHO. AFP case surveillance and polio vaccine immunization work needs to be strengthened.