ε-聚己内酯(PCL)做为生物医用高分子材料,国外已有不少报道,然而国内研究不多,原因是对材料性能要求苛刻且价格昂贵,对于PCL的合成,目前多采用辛酸亚锡和双金属氧桥烷氧化物为引发剂开环聚合。我们采用价格便宜易得的钛酸丁酯为引发剂制得聚合物与其他方法制得的聚合物在结构与性能上无根本的差别,体外缓释性能实验表明,可望做为某些药物的载体加以使用。 ε-polycaprolactone (PCL) as a biomedical polymer materials, there are many foreign reports, but few domestic research, due to demanding and expensive material properties, the synthesis of PCL, the current use of bitterness Stannous and bimetal oxide alkoxylates as ring-opening polymerization initiator. We use cheap and readily available butyl titanate as an initiator polymer obtained by other methods and the polymer obtained in the structure and performance is no fundamental difference in vitro sustained release performance experiments show that it is expected as certain drugs The vector is used.