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目的 :探讨非风湿性心房颤动患者经药物复律后左房收缩功能的改变。方法 :观察了 2 3例患者药物复律第 1、8、15、30及 6 0天时的二尖瓣血流变化并与 2 0例正常人作对比研究。结果 :患者复律后 2周内的左室舒张晚期二尖瓣血流峰速、速度积分显著增大 ,此后 2周内渐大 ,而同期的左室舒张早期血流峰速、速度积分减小 ;与正常人相比 ,患者 1个月、2个月时左室舒张晚期二尖瓣血流仍有显著性不同 (P <0 .0 5 ) ,但两者间无显著性差异。结论 :患者恢复窦性心律后左房收缩功能恢复主要在 1个月内逐步进行 ,且 2个月内不能完全恢复 ,多普勒超声观察有助于指导药物治疗及疗效评价。
Objective: To investigate the changes of left atrial systolic function in patients with non-rheumatic atrial fibrillation after cardioversion. Methods: The changes of mitral blood flow were observed at the first, the eighth, the 15th, the 30th and the 60th days after cardioversion in 23 patients and compared with 20 normal subjects. Results: Within two weeks after cardioversion, peak velocity and velocity integral of mitral flow in left ventricular diastolic phase increased significantly and then became larger in two weeks after cardioversion. In the same period, peak velocity and velocity integral of early diastole Compared with normal subjects, the left ventricular diastolic mitral flow was still significantly different at 1 month and 2 months (P <0.05), but there was no significant difference between the two groups. CONCLUSION: The recovery of left atrial systolic function after sinus rhythm is restored mainly gradually within 1 month, and can not be completely recovered within 2 months. Doppler ultrasound can help to guide the drug treatment and evaluate the curative effect.