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经皮冠状动脉介入术后抗栓治疗十分重要,盐酸替罗非班是经皮冠状动脉介入术后抗栓治疗的重要药物之一。盐酸替罗非班是一种可逆性非肽类血小板GP IIb/IIIa受体拮抗剂,能够作用于血小板聚集的最后通路,有明显的抗栓作用。应用替罗非班的主要不良反应有出血和血小板减少症,通过分析临床应用替罗非班引起极重度血小板减少症1例,为如何防治替罗非班引起血小板减少症提供建议。
Percutaneous coronary intervention after antithrombotic treatment is very important, tirofiban hydrochloride is one of the important drugs for antithrombotic therapy after percutaneous coronary intervention. Tirofiban Hydrochloride is a reversible, non-peptide platelet GP IIb / IIIa receptor antagonist that acts on the last pathway of platelet aggregation with significant antithrombotic effects. One of the major side effects of tirofiban was bleeding and thrombocytopenia. One case of very severe thrombocytopenia caused by clinical use of tirofiban was analyzed to provide advice on how to prevent and treat tirofiban-induced thrombocytopenia.