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氯考胶丸系我院自制制剂,临床上主要用于妇科疾病如阴道炎等的治疗,疗效显著。该制剂具有工艺简单、疗效确切、使用方便等优点。为了控制其制剂质量,我们采用紫外分光光度法,不经分离直接在278nm波长处测定其主要药物氯霉素的含量,该方法操作简便,结果较准确,适合于医院制剂分析,现将其制备过程及含量测定方法报道如下: 一、处方组成及制备方法 1 处方 氯霉素500g、醋酸泼尼松25g、淀粉1000g,共制10000丸。
Chlorophenolate-based self-made capsules in our hospital, clinically mainly for the treatment of gynecological diseases such as vaginitis, a significant effect. The preparation has the advantages of simple process, exact curative effect, convenient use and the like. In order to control the quality of its preparation, we use UV spectrophotometry, without the separation directly measured at 278nm wavelength of its main drug chloramphenicol content, the method is simple, the result is more accurate, suitable for analysis of hospital preparations, now its preparation Process and content determination method reported as follows: First, the prescription and preparation methods 1 prescription chloramphenicol 500g, prednisone acetate 25g, starch 1000g, a total of 10000 pills.