银屑病很少继发皮肤癌,其原因有认为。由于银屑病表皮转换速度加快,癌病灶难于在银屑病皮损内立足;有认为与银屑病患者皮肤和其他组织中芳香烃羟基化酶(AHH)活性降低,致患者对各种环境致癌因子不敏感有关。近十几年来我科收集得银屑病继发皮肤鳞癌五例,一般临床资料见附表: 五名患者中4男1女,发现皮肤癌时年龄最小37岁,最大61岁,平均年龄49.2岁。从患银屑病至发生皮肤癌的平均年限为21.6年。五名患者共发生八个鳞癌病灶,除2个于阴囊外,其余6个癌病灶均发生于 Psoriasis rarely secondary to skin cancer, the reason for that. Due to the accelerated conversion of psoriasis epidermis, cancer lesions are difficult to stand in the psoriatic skin lesions; there is that patients with psoriasis and other tissues of aromatase hydroxylase (AHH) activity decreased, resulting in a variety of environments Not sensitive to carcinogenic factors. In the last ten years, our department has collected 5 cases of squamous cell carcinoma secondary to psoriasis. The general clinical data is shown in the attached table: 4 males and 1 female in 5 patients, the youngest 37 years old, the oldest 61 years old, the average age 49.2 years old. The average age from developing psoriasis to skin cancer is 21.6 years. Five patients had a total of eight squamous cell carcinomas, except two in the scrotum, the remaining six cancerous lesions occurred in