对50例LADA患者4,0例经典(速发性)T1DM患者进行了身高、体重、血糖、空腹和餐后2h C肽、糖化血红蛋白(HbA1c)、甘油三酯(TG)、胆固醇(TC)测定,并计算体重指数(BMI)、胰岛素抵抗指数(HOMA-IR)。结果 LADA组HOMA–IR明显高于T1DM组,空腹C肽与T1DM组近似;餐后2h C肽明显高于T1DM组。结论 LADA患者存在相当程度的胰岛素抵抗,但又有胰岛B细胞功能不足。 The body weight, blood glucose, fasting and postprandial 2h C-peptide, HbA1c, triglyceride (TG) and cholesterol (TC) were measured in 40 patients with classic LADA Measurement and calculation of body mass index (BMI), insulin resistance index (HOMA-IR). Results The HOMA-IR of LADA group was significantly higher than that of T1DM group, while the fasting C peptide was similar to that of T1DM group. The C peptide of postprandial 2h was significantly higher than that of T1DM group. Conclusions There is a considerable degree of insulin resistance in LADA patients, but there are also insufficiency of islet B cells.