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目的 探索一种不受主观因素影响，能客观反映嗅觉功能的实验方法。方法 采用２０只健康家兔，刺激电极分别置于筛板和鼻甲嗅区粘膜及呼吸区粘膜；记录电极置于头皮表面近嗅球部，给予０．２ ～４．０ ｍＡ电刺激，记录产生的诱发电位。结果 电极置于筛板和鼻甲嗅区粘膜可记录到一组“负正负”三相的诱发电位波，依次命名为Ｎ１、Ｐ１ 、Ｎ２ ，当刺激强度为２．０ ｍＡ时，筛板粘膜诱发电位的潜伏期分别为１６．２７ 、２５．３６、４９．７５ ｍｓ； 鼻甲嗅区粘膜诱发电位的潜伏期为２０．２９、３１．３１、４６．８３ｍｓ。电极置于呼吸区粘膜及切断嗅神经后的嗅区粘膜不能引出诱发电位。结论 电刺激家兔嗅粘膜可引出波形稳定的嗅神经诱发电位，该电位源于嗅觉系统。
Objective To explore an experimental method that can objectively reflect olfactory function without being affected by subjective factors. Methods Twenty healthy rabbits were used. The stimulation electrodes were placed on the mucosa and the mucosa of the respiratory tract in the fringe plate and the nasal concha, respectively. The recording electrodes were placed on the surface of the scalp and near the olfactory bulb. The electrodes were electrostimulated at 0.2-4.0 mA. Evoked potentials. Results The electrodes were placed on the sieve plate and turbinate nasal mucosa can be recorded to a group of “negative positive negative” three-phase induced potential wave, followed by named N1, P1, N2, stimulus intensity of 2.0 mA, the sieve The incubation period of mucosal evoked potentials were 16.27, 25.36 and 49.75 ms respectively. The incubation period of mucosal evoked potentials in nasal olfactory mucosa was 20.29, 31.31 and 46.83 ms. The electrode placed in the respiratory area mucosa and cut off olfactory nerve after the olfactory mucosa can not lead to evoked potentials. Conclusion Electrically stimulation of olfactory mucosa in rabbits induces a stable waveform of olfactory nerve evoked potential originating from the olfactory system.