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目的探讨妊娠宫颈癌机会性筛查的应用及其意义。方法对2009年新疆自治区人民医院妇产科门诊就诊的自愿接受筛查的维吾尔族孕妇组、进行健康体检的妇女组,分别进行宫颈癌HPV+宫颈液基细胞学的筛查,评价妊娠期宫颈癌机会性筛查在宫颈癌早诊早治中的意义。结果产前检查知晓率的为98%宫颈癌筛查知晓率的为74%,受检妊娠妇女无1例发生流产,仅1例发生早产,两组HPV检出率相比,差异有统计学意义(χ2=32.13,P<0.05),宫颈病变检出率相比差异无统计学意义(P>0.05)。HPV的转阴率为71%,ASCUS的转阴率为98%。结论妊娠期机会性筛查与非妊娠期相比,是安全、必要、有效的,值得推广应用。
Objective To investigate the application and significance of opportunistic screening of cervical cancer in pregnancy. Methods The Uygur pregnant women who were volunteered for screening in Obstetrics and Gynecology Clinic of People’s Hospital of Xinjiang Uygur Autonomous Region in 2009 and the women who underwent physical examination were screened for cervical cancer HPV + cervical liquid-based cytology and evaluated for gestational cervical cancer Significance of opportunistic screening in early diagnosis and treatment of cervical cancer. Results The awareness rate of prenatal examination was 98%, 74% of cervical cancer screening rate. None of the pregnant women under test had abortion, only one case had premature birth. There was statistically significant difference in HPV detection rate between the two groups Significance (χ2 = 32.13, P <0.05), no significant difference in the detection rate of cervical lesions (P> 0.05). The negative conversion rate of HPV was 71% and that of ASCUS was 98%. Conclusion Compared with non-pregnant period, opportunistic screening in pregnancy is safe, necessary and effective, which is worthy of popularization and application.