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目的比较地塞米松、氟哌利多对小儿术后恶心呕吐的预防作用。方法100例ASAⅠ～Ⅱ级手术患儿于全麻(气管插管组和非气插管组)下随机分为地塞米松组和氟哌利多组,每组各25例。于麻醉诱导前1min,试验组给予地塞米松(Ⅰ组)0.1～0.2mg/kg(最大量不超过5mg),对照组给予氟哌利多75μg/kg,观察注药后2h内每30min心率、血压、血氧饱和度、病人恶心呕吐发生次数。结果Ⅰ组无低血压发生,恶心呕吐低于Ⅱ组。结论地塞米松可有效降低小儿术后恶心呕吐发生且明显强于氟哌利多。
Objective To compare the preventive effect of dexamethasone and droperidol on postoperative nausea and vomiting in children. Methods 100 children with ASA Ⅰ ~ Ⅱ operation were randomly divided into dexamethasone group and droperidol group under general anesthesia (tracheal intubation group and non-intubation group), 25 cases in each group. At 1 minute before induction of anesthesia, dexamethasone (group Ⅰ) 0.1-0.2 mg / kg (maximally 5 mg) was given to the experimental group and droperidol 75 μg / kg. The control group was given 30 min of heart rate within 2 hours after injection. Blood pressure, oxygen saturation, nausea and vomiting occurred in patients. Results No hypotension occurred in group Ⅰ, and nausea and vomiting were lower than those in group Ⅱ. Conclusion Dexamethasone can effectively reduce the incidence of postoperative nausea and vomiting in children and is significantly stronger than droperidol.