目的探讨治疗生殖道解脲支原体感染的有效方法。方法对120例解脲支原体阳性患者用口服多西环素,一疗程为10天;多西环素+罗红霉素或左氧氟沙星注射液,洁康洗液坐浴,连用7～8天。停药7天后复查解脲支原体加药敏。结果女性和男性患者中,一疗程治愈率分别为93%和85%,余5%和10%为二疗程治愈,2%和5%为三疗程治愈。结论对解脲支原体感染患者要从单一用药开始,对较顽固的支原体感染患者采用联合用药效果更好。 Objective To investigate the effective method of treating genital Ureaplasma urealyticum infection. Methods 120 cases of Ureaplasma urealyticum positive patients with oral doxycycline, a course of 10 days; doxycycline + roxithromycin or levofloxacin injection, Jie Kang lotion bath, once every 7 to 8 days. Ureaplasma Ureaplasma plus drug-susceptibility test after 7 days withdrawal. Results Female and male patients, a cure rate was 93% and 85%, respectively, and 5% and 10% for the second course of treatment was cured, 2% and 5% for three courses of treatment. Conclusion For UU-infected patients, the combination therapy should be better than the single-drug therapy for patients with more persistent Mycoplasma infection.