目的了解洛阳市男男性行为者(MSM)新型毒品使用情况及其相关因素,为MSM艾滋病防治策略制定提供科学依据。方法应用滚雪球方法招募洛阳市MSM作为研究对象,进行匿名问卷调查,内容包括MSM的社会人口学特征、性行为特征、新型毒品使用情况等。应用χ~2检验和非条件Logistic回归分析新型毒品使用对高危性行为的影响以及新型毒品使用的影响因素。结果 2016年5-10月,共招募MSM 1 010人,平均年龄(27.2±7.3)岁,新型毒品使用率为79.4%(802/1 010),新型毒品使用后,MSM安全套使用率较低,发生群交行为的比例较高。单因素分析结果显示,年龄、婚姻、文化程度、月收入以及性取向是未感染艾滋病病毒(HIV)的MSM新型毒品使用的影响因素。多因素Logistic回归结果显示,文化程度比值比(OR):1.72,95%可信区间(CI):1.37~2.17)、月均收入水平(OR:0.38,95%CI:0.26~0.54)和婚姻状况(OR:0.57,95%CI:0.40~0.80)是新型毒品使用的影响因素。结论洛阳市MSM新型毒品使用比例高,新型毒品使用可显著增加HIV感染高危行为的发生。加强新型毒品使用的危害性和警示性宣传应成为MSM行为干预的重要内容,可减少HIV新发感染的发生。 Objective To understand the use of new drugs and their related factors in MSM in Luoyang and provide a scientific basis for the development of AIDS prevention and control strategies in MSM. Methods The snowball method was used to recruit MSM in Luoyang as an object of study. Anonymous questionnaires were conducted to investigate the socio-demographic characteristics of MSM, the characteristics of sexual behaviors and the use of new drugs. The χ ~ 2 test and non-conditional logistic regression analysis were used to analyze the impact of new drug use on high-risk behaviors and the influencing factors of new drug use. Results From May to October 2016, a total of 1,010 MSMs were recruited, with an average age of (27.2 ± 7.3) years. The new drug use rate was 79.4% (802/1 010). After the new drugs were used, the MSM condom use rate was low, The incidence of group behavior is higher. Univariate analysis showed that age, marital status, education level, monthly income and sexual orientation were the influencing factors for the new drug use of MSM without HIV infection. Multivariate logistic regression analysis showed that educational level odds ratio (OR) was 1.72, 95% confidence interval (CI): 1.37-2.17), monthly average income (OR: 0.38, 95% CI: 0.26-0.54) The status (OR: 0.57, 95% CI: 0.40-0.80) was the influencing factor of new drug use. Conclusion The new drug use rate of MSM in Luoyang is high, and the use of new drug can significantly increase the high risk behaviors of HIV infection. Enhancing the harmful and alert publicity of the use of new drugs should be an important part of MSM behavioral interventions to reduce the incidence of new HIV infections.