论文部分内容阅读
目的探析老年肾综合征出血热(HFRS)患者流行病学、临床特征及预后等方面的特点。方法选取2013年8月-2015年8月在我院诊治的245例肾综合征出血热患者,将其依据年龄段划分为青年组(<40岁,81例)和老年组(≥60岁,28例)。就两组预后、实验室检查、临床特征及流行病学等予以回顾性分析及比较。结果老年组危重型及重型患者为11例(39.29%),青年组为15例(18.52%),两组比较差异显著(P<0.05)。老年组早期误诊率相比于对青年组,高于后者且差异显著(P<0.05)。青年组在多尿期、少尿期及发热期持续时间相比于老年组,均短于后者且差异显著(P<0.05)。老年组血小板降低及肌酐升高幅度相比于青年组,均优于后者且差异明显(P<0.05),老年组白细胞、尿素氮、谷丙转氨酶及谷草转氨酶相比于青年组,所存差异不明显,无统计学意义(P>0.05)。两组于治疗当中,青年组出现并发症为7例(8.64%),老年组为12例(42.86%),两组比较差异存在统计学意义(P<0.05)。老年组病死率相比于青年组,高于后者且差异显著(P<0.05)。结论针对老年肾综合征出血热患者,其相比于青年HFRS患者,早期具有误诊率,且具有较高的重型及危重型比例,并发症多,长病症。
Objective To analyze the epidemiology, clinical characteristics and prognosis of elderly patients with hemorrhagic fever with renal syndrome (HFRS). Methods A total of 245 patients with hemorrhagic fever with renal syndrome who were diagnosed and treated in our hospital from August 2013 to August 2015 were divided into four groups according to their ages: young group (<40 years old, 81 cases) and elderly group (≥60 years old, 28 cases). On the two groups of prognosis, laboratory tests, clinical features and epidemiology were retrospectively analyzed and compared. Results There were 11 cases (39.29%) in the elderly group and 15 cases (18.52%) in the young group. There was significant difference between the two groups (P <0.05). The early misdiagnosis rate in elderly group was higher than that in young group (P <0.05). The duration of oliguria and fever in the youth group was shorter than that in the elderly group (P <0.05). Compared with the young group, the decrease of thrombocytopenia and the increase of creatinine in the elderly group were superior to the latter group (P <0.05). The difference of the white blood cells, urea nitrogen, alanine aminotransferase and aspartate aminotransferase in the elderly group Not obvious, no statistical significance (P> 0.05). Among the two groups, there were 7 cases (8.64%) in the young group and 12 cases (42.86%) in the old group. The difference between the two groups was statistically significant (P <0.05). The mortality rate in the elderly group was higher than that in the young group (P <0.05). Conclusion Hemorrhagic fever with senile renal syndrome (HFRS) patients has a higher rate of misdiagnosis compared with young HFRS patients and has a higher proportion of severe and critically ill patients with multiple complications and long illness.