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约20%的恶性肿瘤患者伴有高血糖,在切除或缩小肿瘤负荷后,部分患者高血糖可得到缓解甚至恢复正常。荷瘤机体的应激反应与胰岛素抵抗关系密切,通常与肿瘤异位产生胰岛素的拮抗激素,机体/肿瘤组织产生炎性细胞因子影响胰岛素敏感性有关。长期高血糖状态致线粒体呼吸膜受损,糖酵解加强,为肿瘤细胞的增殖提供营养基。恶性肿瘤组织合成代谢所需能量(三磷酸腺
About 20% of malignant tumor patients with hyperglycemia, resection or reduce the tumor burden, some patients with hyperglycemia can be relieved or even returned to normal. Tumor-bearing body’s stress response and insulin resistance are closely related, usually with the ectopic tumor-producing insulin antagonist hormones, body / tumor tissue inflammatory cytokines affect insulin sensitivity. Long-term hyperglycemia caused by mitochondrial respiratory membrane damage, glycolysis to strengthen, provide the basis for the proliferation of tumor cells. Malignant tumor tissue anabolic energy required (triphosphate gland