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目的 :探讨静脉营养支持在先天性食管闭锁围手术期的应用。方法 :11例TPN组患儿在围手术期输注全营养液 ,平均热量摄入 64± 11kcal/kg/d ,9例对照组患儿输注葡萄糖及血浆 ,平均热量摄入 3 9± 8kcal/kg/d。结果 :TPN组TPN前后血浆总蛋白、白蛋白无下降 ,体重平均增加 16± 2 4g/d。对照组治疗前后血浆总蛋白、白蛋白下降 ,体重平均减少 2 1± 3 2g/d。两组体重变化、并发症发生率及病死率均有显著性差异 (P <0 0 1,P <0 0 5 )。结论 :合理的TPN能改善食管闭锁患儿的营养状况 ,维持并促进体重的增加 ,减少并发症 ,改善预后。合理应用TPN是安全的
Objective: To investigate the application of intravenous nutritional support during perioperative period of congenital esophageal atresia. Methods: Eleven patients with TPN were infused with perioperative nutrient solution. The average calorie intake was 64 ± 11 kcal / kg / d. Nine children in the control group received glucose and plasma infusion. The average calorie intake was 39 ± 8 kcal / kg / d. Results: TPN before and after TPN plasma total protein, albumin no decline, an average increase in body weight 16 ± 2 4g / d. Before and after treatment in the control group, total plasma protein and albumin decreased, with an average weight loss of 21 ± 32 g / d. There were significant differences in body weight, complication rate and mortality between the two groups (P <0.01, P <0.05). Conclusion: A reasonable TPN can improve nutritional status of children with esophageal atresia, maintain and promote weight gain, reduce complications and improve prognosis. Proper use of TPN is safe