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目的:观察干扰素联合拉米呋啶治疗慢性乙肝的效果。方法:用干扰素联合拉米呋啶治疗慢性乙肝30例,与单用苦参素治疗30例进行随机对照观察。结果:治疗结束后,联合治疗组HBeAg阴转率及HBVDNA阴转率均显著高于单用苦参素组。结论:干扰素联合拉米呋啶治疗慢性乙肝可提高疗效。
Objective: To observe the effect of interferon plus lamivudine in the treatment of chronic hepatitis B. Methods: Thirty patients with chronic hepatitis B treated with interferon plus lamivudine and 30 patients treated with oxymatrine alone were randomized and controlled. Results: After the treatment, the negative conversion rate of HBeAg and negative rate of HBVDNA in the combined treatment group were significantly higher than those in the single oxymatrine group. Conclusion: Interferon combined with lamivudine in the treatment of chronic hepatitis B can improve the curative effect.