目的总结胰腺实性假乳头状瘤的临床特点及诊治体会。方法回顾性分析2000年5月至2010年5月期间在我科手术治疗并经病理检查证实的8例胰腺实性假乳头状瘤患者的临床资料。结果 3例肿瘤位于胰头部者行胰十二指肠切除术;2例肿瘤位于胰颈部者行单纯肿瘤摘除术;1例肿瘤位于胰体部者行胰腺中段切除、近端闭合、远端与空肠行吻合术;2例位于胰尾部者行胰体尾切除联合脾脏切除术。术中未见腹腔脏器转移。8例患者术后经病理检查均证实为胰腺实性假乳头状瘤。术后均未行放、化疗。本组患者随访1~10年(平均5.5年),除2例失访外,其余均健在。结论 胰腺实性假乳头状瘤临床少见,属低度恶性肿瘤,女性多见;CT及MRI是其主要的影像学检查手段;手术切除预后较好。 Objective To summarize the clinical features, diagnosis and treatment of pancreatic pseudopapillary tumor. Methods The clinical data of 8 patients with solid pseudopapillary pancreatic tumors of the pancreas confirmed by pathological examination from May 2000 to May 2010 in our department were retrospectively analyzed. Results Three cases of tumors located in the head of the pancreas underwent pancreatoduodenectomy. Two cases of tumors located in the pancreas and neck were treated with simple tumor excision. One case of tumor located in the body of the pancreas was resected in the middle of the pancreas and the proximal end was closed. End and jejunum line anastomosis; 2 cases located in the tail of the pancreas pancreatic tail resection combined with splenectomy. No intraoperative abdominal organ metastasis. All 8 patients were proved to be pancreatic pseudopapillary tumors by pathological examination. No postoperative radiotherapy and chemotherapy. The patients were followed up for 1 to 10 years (mean 5.5 years), except for 2 patients lost, the rest are alive. Conclusions Solid pseudopapillary pancreatic tumors are rare in clinical practice. They are low-grade malignant tumors and are more common in women. CT and MRI are the main means of imaging examination. The prognosis of surgical resection is good.