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目的:观察B超或CT引导下微波消融治疗肝癌的临床效果及安全性。材料与方法:选择48例原发性肝癌和肝转移瘤患者共57个病灶,在影像引导下行微波消融治疗,观察临床症状及AFP变化情况,通过强化CT、MR或数字减影血管造影(DSA)了解病灶消融程度,随访治疗后1、2、3年生存率。结果:术前23例甲胎蛋白>400μg/L者,术后1月复查21例下降,其中15例降至正常值范围。57个病灶完全坏死占84.21%(48/57),不完全坏死8.77%(5/57),部分坏死7.01%(4/57)。1、2、3年生存率分别为77.08%(37/48)、64.58%(31/48)、39.58%(19/48)。全组无严重并发症及手术死亡发生。结论:影像引导下的微波消融治疗肝癌具有疗效确切、创伤小、安全性高、操作简便的优势,是肝癌的有效微创疗法之一。
Objective: To observe the clinical effect and safety of microwave ablation guided by B-ultrasound or CT. Materials and Methods: Forty-seven patients with primary hepatocellular carcinoma (HCC) and liver metastases were selected. Fifty-seven lesions were selected and underwent microwave ablation guided by imaging. Clinical symptoms and changes of AFP were observed. CT, MR, or digital subtraction angiography ) To understand the degree of lesion ablation, follow-up treatment 1, 2, 3-year survival rate. Results: Preoperative 23 cases of alpha-fetoprotein> 400μg / L, 21 cases were rechecked in January after the fall, of which 15 cases fell to the normal range. Complete necrosis of 57 lesions accounted for 84.21% (48/57), incomplete necrosis 8.77% (5/57), partial necrosis 7.01% (4/57). The 1, 2, 3 year survival rates were 77.08% (37/48), 64.58% (31/48) and 39.58% (19/48), respectively. The whole group without serious complications and surgical death occurred. Conclusion: Microwave-guided microwave ablation is an effective and minimally invasive method for the treatment of liver cancer with the advantages of effective curative effect, small trauma, high safety and easy operation.