目的:评价岩舒注射液联合吉西他滨+奥沙利铂治疗晚期胰腺癌的临床疗效。方法:50例晚期胰腺癌患者随机分为治疗组(30例)和对照组(20例),两组均用吉西他滨+奥沙利铂化疗,治疗组同时加用岩舒注射液。结果:治疗组和对照组有效率分别为66.67%和50.00%,两组比较无显著性差异(P>0.05);治疗组生存质量明显优于对照组,差异有统计学意义(P<0.05)。结论:岩舒注射液联合吉西他滨、奥沙利铂治疗晚期胰腺癌安全、有效,在改善生活质量特别是控制癌痛方面具有一定优势。 Objective: To evaluate the clinical efficacy of Yan Shu injection plus gemcitabine + oxaliplatin in the treatment of advanced pancreatic cancer. Methods: Fifty patients with advanced pancreatic cancer were randomly divided into treatment group (n = 30) and control group (n = 20). Both groups were treated with gemcitabine plus oxaliplatin. The treatment group was treated with Yan Shu injection. Results: The effective rates of the treatment group and the control group were 66.67% and 50.00%, respectively, with no significant difference between the two groups (P> 0.05). The quality of life of the treatment group was significantly better than that of the control group (P <0.05) . Conclusion: Yanshu injection combined with gemcitabine and oxaliplatin in the treatment of advanced pancreatic cancer is safe and effective, and has certain advantages in improving quality of life, especially in controlling cancer pain.