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在探讨药物的毒性,进行中草药的实验研究时,有时需要求半数有效量(ED_(50))或半数致死量(LD_(50))。半数有效量(简称半效量),是指一批同等条件的动物,经过施用药物或某种处理后,有半数能抵抗某种疾病或症状。计算半效量的方法很多,常用的有寇氏法,改进寇氏法,简化机率单位法,图解法,面积法,角变换法,累计法,移动平均法,
In order to explore the toxicity of drugs and to carry out experimental research on Chinese herbal medicine, it is sometimes necessary to find the effective dose (ED_ (50)) or the median lethal dose (LD_ (50)). Half of the effective amount (referred to as half effective amount), refers to a group of animals of the same conditions, after the application of drugs or a treatment, half can resist a disease or symptoms. There are many ways to calculate the half effective amount. Commonly used are Kou’s method, improved Kou’s method, simplified probability unit method, graphic method, area method, angular transformation method, accumulative method, moving average method,