目的分析上海市普陀区2009-2015年疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)的监测结果。方法收集AEFI信息管理系统中2009-2015年报告的AEFI个案数据,采用描述流行病学方法进行分析。结果 2009-2015年普陀区共报告AEFI个案5 476例,报告街镇覆盖率为100%;个案完整率为100%,48小时内报告率为99.07%,48小时内调查率为99.96%。AEFI报告率为195.57/10万剂,呈上升趋势,差异有统计学意义。第一类疫苗AEFI报告率为186.52/10万剂,第二类疫苗AEFI报告率为217.99/10万剂,差异有统计学意义。结论普陀区AEFI监测系统运行情况良好,AEFI报告率逐步提高。可开展主动监测了解不同疫苗分类的AEFI发生情况。 Objective To analyze the surveillance results of Adverse Events Following Immunization (AEFI) from 2009 to 2015 in Putuo District, Shanghai. Methods AEFI case data collected during the 2009-2015 report of the AEFI information management system was collected and analyzed using descriptive epidemiological methods. Results A total of 5 476 AEFI cases were reported in Putuo District from 2009 to 2015, covering 100% of the towns in the town. The case complete rate was 100%. The report rate was 99.07% in 48 hours and 99.96% in 48 hours. AEFI report rate of 195.57 / 10 million doses, an upward trend, the difference was statistically significant. The first type vaccine AEFI report rate was 186.52 / 10 million doses, the second type vaccine AEFI report rate was 217.99 / 10 million doses, the difference was statistically significant. Conclusion The AEFI monitoring system in Putuo District operated well and the AEFI reporting rate gradually increased. Proactive monitoring can be conducted to understand the occurrence of AEFI in different vaccine categories.