目的　观察晚期肝炎肝硬化早期抗感染干预措施的临床效果。方法　回顾性分析 98例患者 ,分为治疗组及对照组 ,其中对照组 42例 ,没有采取早期抗感染干预措施 ,严格无菌操作 ,在有感染征象时根据药敏使用抗菌药物 ;观察组 5 6例使用早期抗感染干预措施 ,其余治疗方法基本相同。结果　观察组 8例发生感染 (占 14 .3 %) ,对照组有 19例发生感染 (占 45 .2 %) ,x2 =11.5 19,P <0 .0 1,具有统计学意义 ,相对危险度为 3 .16。感染控制失败率 :观察组 1例 (占12 .5 %) ,对照组 11例 (占 5 7.9%) ,u =2 .168>1.96,P <0 .0 5 ,具有统计学意义。结论　晚期肝炎肝硬化早期抗感染干预措施的临床效果较为明显 Objective To observe the clinical effect of early anti-infective intervention in advanced cirrhosis of liver. Methods A retrospective analysis of 98 patients, divided into treatment group and control group, of which 42 cases in the control group, did not take early anti-infective interventions, strict aseptic operation, in the presence of signs of antimicrobial agents based on drug susceptibility; observation group 5 Six cases used early anti-infective interventions, and the rest of the treatment was basically the same. Results In the observation group, infection was found in 8 cases (14.3%) and infection in the control group (45.2%), x2 = 11.519, P <0.01, with statistical significance and relative risk Is 3.16. Infection control failure rate: 1 case (12.5%) in the observation group, 11 cases (5 7.9%) in the control group, u = 2.168> 1.96, P <0.05, with statistical significance. Conclusion The clinical effect of early anti-infective interventions in patients with advanced liver cirrhosis is more obvious