【摘 要】
：
The regioselective acylation of quercetin catalyzed by a novel thermophilic esterase(APE1547)from the archaeon Aeropyrum pernix K1 was successfully conducted in
【机 构】
：
The First Hospital of Jilin University,Key Laboratory for Molecular Enzymology and Engineering,Colle
【基金项目】
：
国家自然科学基金;the Natural Science Foundation of Jilin Province,China
论文部分内容阅读
The regioselective acylation of quercetin catalyzed by a novel thermophilic esterase(APE1547)from the archaeon Aeropyrum pernix K1 was successfully conducted in organic solvents.The effects of acyl donor,substrate ratio,organic solvent,temperature,and water activity were investigated.Under the optimum conditions,a yield of 74％ for its mono ester could be achieved in the reaction for about 6 h.With the reaction time extending to about 30 h,the final conversion of quercetin was about 100％ and three products were synthesized.
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