原发性硬化性胆管炎(PSC)是原因不明的慢性进行性胆汁郁积病。其特征为肝内、外胆管的炎性反应,纤维化和部分胆管丧失,致胆管节段性狭窄和扩张,胆管造影呈串珠状改变。其临床证侯以黄疸、搔痒和右上腹痛,吸收不良和厌食致体质量减轻。有伴发热、乏力。相当于祖国医学中“胁痛” Primary sclerosing cholangitis (PSC) is an unexplained chronic progressive cholestasis. It is characterized by intrahepatic and extrahepatic bile duct inflammatory reactions, fibrosis and the loss of some bile duct, resulting in segmental stenosis and dilatation of the bile duct, bile duct angiography beaded change. The clinical card Hou to jaundice, itching and right upper quadrant pain, malabsorption and anorexia induced body mass reduction. With fever, fatigue. Equivalent to the motherland medicine “Xie pain”