生长抑素(Somatostatin,SST)为一种14肽,1973年Brazeau等首先从牛下丘脑分离并描述其特性,免疫组织化学研究证明它广泛地分布于大鼠中枢神经系统中。有人报道它可能是痛传递递质,也有人认为它可能是痛调制物。近年来有人于椎管内或硬膜外注射SST,用以治疗癌症疼痛及手术后疼痛。作者用大鼠进行动物实验研究,进一步观察SST椎管内给药时产生的剂量依赖性抗 Somatostatin (SST), a 14-peptide, was first isolated and characterized by Brazeau et al. In 1973 from the bovine hypothalamus. Immunohistochemical studies have shown that it is widely distributed in the central nervous system of rats. It has been reported that it may be painful delivery of transmission, some people think it may be pain modulation. In recent years, someone in the spinal canal or epidural injection of SST, for the treatment of cancer pain and postoperative pain. The authors used animal experiments in rats to further observe the dose-dependent anti-SST