论文部分内容阅读
目的:探讨幽门螺杆菌感染对孕妇子痫前期发病及母儿结局的影响。方法:随机选择284例孕周>20周的孕妇分为幽门螺杆菌感染阴性组和幽门螺杆菌感染阳性组。跟踪观察、记录子痫前期(轻度子痫、重度子痫)发病及母儿结局(胎盘早剥、产后大出血、胎儿窘迫、围产儿死亡、胎盘重量、1 min新生儿Apgar评分、胎龄及新生儿体重)情况,进行比较分析。结果:281例(阴性组148例,阳性组133例)纳入统计。除胎盘早剥、产后大出血、胎儿窘迫、围产儿死亡率外,阴性组与阳性组的轻度子痫、重度子痫、胎盘重量、1 min Apgar评分、胎龄及新生儿体重差异均有统计学意义(均P<0.05),阴性组母儿结局优于阳性组。幽门螺杆菌感染与轻度子痫发病、重度子痫发病呈正相关(均P<0.05);幽门螺杆菌感染与胎盘重量、1 min Apgar评分、胎龄及新生儿体重均呈负相关(均P<0.05)。结论:幽门螺杆菌感染与孕妇子痫前期发病有密切的关系,幽门螺杆菌感染对母儿结局具有不良的影响。
Objective: To investigate the influence of Helicobacter pylori infection on maternal preeclampsia and maternal and infant outcomes in pregnant women. Methods: A total of 284 pregnant women with gestational weeks> 20 weeks were randomly divided into H. pylori negative group and H. pylori positive group. The incidence of preeclampsia (mild eclampsia, severe eclampsia) and maternal and infant outcomes (placental abruption, postpartum hemorrhage, fetal distress, perinatal death, placental weight, Apgar score at 1 min, gestational age and Newborn weight) situation, comparative analysis. Results: 281 cases (negative group 148 cases, positive group 133 cases) were included in the statistics. In addition to placental abruption, postpartum hemorrhage, fetal distress, perinatal mortality, the negative group and the positive group mild eclampsia, severe eclampsia, placental weight, 1 min Apgar score, gestational age and neonatal body weight differences were statistically Significance (both P <0.05), the negative group of maternal outcomes than the positive group. Helicobacter pylori infection was positively correlated with mild eclampsia and severe eclampsia (all P <0.05). Helicobacter pylori infection was negatively correlated with placental weight, Apgar score at 1 minute, gestational age and neonatal body weight (P <0.05). Conclusion: Helicobacter pylori infection is closely related to the incidence of preeclampsia in pregnant women. Helicobacter pylori infection has adverse effects on the outcomes of both maternal and infant.