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1例38岁女性,因胆囊结石,慢性胆囊炎急性发作入院。给予头孢曲松钠2.0g溶入0.9%氯化钠注射液250ml中静脉滴注治疗。静脉滴注药液约150ml后,患者出现手足搐搦、烦躁等症状,其血钙为1.85mmol/L,血钠、血钾,肝肾功能及血糖均正常。立即停药,给予抗过敏及对症治疗不见好转。给予10%葡萄糖酸钙注射液10ml加入25%葡萄糖注射液20ml中静脉注射,45min后上述症状逐渐缓解,8h后血钙升至2.35mmol/L。第2天头孢曲松钠改为氨苄青霉素,上述症状未再出现。
A 38-year-old woman was admitted to hospital for acute episodes of cholecystolithiasis and chronic cholecystitis. Give ceftriaxone 2.0g dissolved in 0.9% sodium chloride injection 250ml intravenous infusion. Intravenous infusion of liquid about 150ml, patients with tetany, irritability and other symptoms, the blood calcium 1.85mmol / L, serum sodium, potassium, liver and kidney function and blood glucose were normal. Immediate withdrawal, given anti-allergy and symptomatic treatment did not improve. Give 10% calcium gluconate injection 10ml 25% glucose injection 20ml intravenous injection, 45min after the above symptoms gradually eased, serum calcium rose to 2.35mmol / L after 8h. The second day ceftriaxone to ampicillin, the above symptoms no longer appear.