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目的:评价6种抗菌药物方案治疗细菌性肺炎的成本.效果。方法:将214例细菌性肺炎患者随机分为6组(A、B、C、D、E、F),分别给予哌拉西林他唑巴坦+阿米卡星、左氧氟沙星、头孢由松、克林霉素、美洛西林、阿奇霉素,观察各组疗效并进行成本-效果分析。结果:6组患者总有效率分别为91.42%,83.33%,89.19%,78.79%,81.08%,77.78%(P>0.05);6种治疗方案总成本分别为2 795.17,1 438.79,1 350.05,1 796.75,1 769.64,1267.89元;成本-效果比分别为30.57,17.33,15.14,22.80,21.83,16.30;以F组为参熙的增量成本-效果比为111.97,30.79,7.20,523.62,152.04,……。结论:头孢曲松钠治疗细菌性肺炎较佳。
Objective: To evaluate the cost and effectiveness of six antibacterials regimens in the treatment of bacterial pneumonia. Methods: A total of 214 patients with bacterial pneumonia were randomly divided into 6 groups (A, B, C, D, E and F). Piperacillin and tazobactam plus amikacin, levofloxacin, Lincomycin, mezlocillin and azithromycin. The curative effect of each group and the cost-effectiveness analysis were observed. Results: The total effective rates of the 6 groups were 91.42%, 83.33%, 89.19%, 78.79%, 81.08% and 77.78% respectively (P> 0.05). The total cost of the 6 treatments were 2 795.17, 1 438.79 and 1 350.05 respectively, 1 796.75,1 769.64,1267.89 yuan; cost-effectiveness ratio was 30.57,17.33,15.14,22.80,21.83,16.30; F group as Senate’s incremental cost-effect ratio of 111.97,30.79,7.20,523.62,152.04 , .... Conclusion: Ceftriaxone sodium treatment of bacterial pneumonia is better.