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调节胆固醇代谢增强CD8+T细胞的抗肿瘤反应中国科学院上海生命科学研究院许琛琦研究员与李伯良研究员合作,在提高T细胞抗肿瘤免疫功能的研究方面取得重要进展,研究结果发表于《自然》杂志。人体的免疫系统负责保卫机体健康,其中T淋巴细胞是获得性免疫系统中重要的功能细胞,负责识别抗原,并协同其他免疫细胞进行免疫应答,然而肿瘤细胞能够通过多种机制抑制T细胞的抗肿瘤活性,从而逃逸
Regulating Cholesterol Metabolites and Increasing Antitumor Response of CD8 + T Cells Xu Cuiqi, a researcher at Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, has collaborated with Dr. Li Bailiang to make important progress in enhancing the anti-tumor immune function of T cells. The findings were published in “Nature” magazine. The body’s immune system is responsible for protecting the body’s health. Among them, T lymphocytes are important functional cells in the acquired immune system and are responsible for recognizing antigens and cooperating with other immune cells for immune response. However, tumor cells can inhibit T cell antigens through various mechanisms Tumor activity, which escapes