周围神经损伤的修复是创伤外科难题之一,筛选理想的促进神经再生移植物,是解决这一难题的关键。近年来,采用脱细胞处理的同种异体神经作为移植物用于周围神经缺损修复已能取得促进神经再生的效果,应用前景较好。笔者就脱细胞神经基质制备的发展进程、各种制备方法的优缺点及试剂选择作一综述。 Peripheral nerve injury repair is one of the traumatic surgical problems, screening the ideal nerve regeneration of the graft, is the key to solve this problem. In recent years, the use of acellular decellularized allogeneic nerve as a graft for peripheral nerve defect repair has been able to achieve the effect of promoting nerve regeneration, the application of good prospects. The author on the development of acellular nerve matrix preparation process, the advantages and disadvantages of various preparation methods and reagent selection are reviewed.