为寻找一种抗雌索性质的抗生育药物,本文每日用200μg、400μg及2000μg不同剂量的氯蔗酚胺,分别给交配后第1,第3及第6天的大鼠服用,连续5d。发现交配后第1及第3天服各种剂量药物的雌鼠均未妊娠,而于交配后第6天服药的各组大鼠与对照组一样均有妊娠。提示氯蔗酚胺对在输卵管阶段的大鼠配子有杀灭作用,而对种植后的胚泡则无抗生育作用。 In order to find an anti-fertility drug with anti-female properties, 200 μg, 400 μg, and 2000 μg of pomelodolamine were administered daily to rats on the first, third, and sixth days after mating, for consecutive 5 days. . It was found that females that took various doses of drug on the first and third day after mating were not pregnant, and that each group of rats that took the drug on the sixth day after mating had the same pregnancy as the control group. It is suggested that the chloropharmacin has a killing effect on the rat gametes in the fallopian tube stage, but has no antifertility effect on the blastocyst after implantation.