目的： 研究清开灵注射液、α干扰素（ αｉｎｔｅｒｆｅｒｏｎ，αＩＮＦ） 和γ干扰素（γｉｎｔｅｒｆｅｒｏｎ，γＩＮＦ） 对翼状胬肉成纤维细胞体外增殖的影响。方法： 用组织培养技术建立翼状胬肉成纤维细胞系。用ＭＴＴ比色法测定清开灵注射液、αＩＮＦ和γＩＮＦ对翼状胬肉成纤维细胞增殖的影响。结果： 清开灵注射液、αＩＮＦ和γＩＮＦ可以明显抑制翼状胬肉成纤维细胞的增殖， 并呈剂量依赖效应。结论： 清开灵注射液、αＩＮＦ和γＩＮＦ均能有效抑制体外翼状胬肉成纤维细胞的生长。 Objective: To study the effects of Qingkailing Injection, αinterferon (αINF) and γinterferon (γINF) on the proliferation of pterygium fibroblasts in vitro. Methods: Tissue culture technique was used to establish pterygium fibroblast cell line. MTT colorimetric determination Qingkailing injection, α  INF and γINF on the proliferation of pterygium fibroblasts. Results: Qingkailing injection, αINF and γINF can significantly inhibit the proliferation of pterygium fibroblasts, and a dose-dependent effect. Conclusion: Qingkailing injection, αINF and γINF can effectively inhibit the growth of pterygium fibroblasts in vitro.