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目的：检测房间隔缺损（ＡＳＤ）、室间隔缺损（ＶＳＤ）和二尖瓣狭窄（ＭＳ）的患者红细胞中ＳＯＤ活力，分析术后ＳＯＤ活力的变化。方法：应用四氮唑蓝法（ＮＢＴ法）。结果：ＡＳＤ、ＶＳＤ和ＭＳ患者红细胞中ＳＯＤ活力明显低于正常人，术后可见ＳＯＤ活力逐步提高，患者年龄愈小，ＳＯＤ活力增加幅度愈大。结论：ＡＳＤ、ＶＳＤ和ＭＳ患者术后可使ＳＯＤ活力增加，有利于保护心脏正常功能。
Objective: To detect the SOD activity of erythrocytes in patients with atrial septal defect (ASD), ventricular septal defect (VSD) and mitral stenosis (MS), and analyze the changes of postoperative SOD activity. Methods: The application of tetrazolium blue method (NBT method). Results: The activity of SOD in erythrocytes in patients with ASD, VSD and MS was significantly lower than that in normal people. After operation, the activity of SOD gradually increased. The younger the patients, the greater the increase of SOD activity. Conclusion: The activity of SOD in ASD, VSD and MS patients can be increased after operation, which is helpful to protect normal heart function.