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目的为临床药师对假膜性肠炎患者进行药学监护提供参考。方法回顾1例临床药师参与的假膜性肠炎患者的救治过程,临床药师建议:停用所有抗菌药物,加用甲硝唑、万古霉素;抗菌药物和蒙脱石散分别与布拉酵母菌散间隔2 h服用,蒙脱石散要用低于40℃的温开水服用;告知患者口服万古霉素对肾功能无影响;控制感染后采用大环内酯类或氨基糖苷类。结果医师和患者采纳了临床药师的建议,经过抗菌药物、微生态制剂、止泻剂的治疗,患者排便、体温、血常规均恢复正常。结论临床药师的有效干预和药学监护,对假膜性肠炎的预防和治疗具有重要意义。
Objective To provide a reference for clinical pharmacists to carry out pharmacy care in patients with pseudomembranous enteritis. Methods One case of pseudophakic enteritis in clinical pharmacists was reviewed. Clinical pharmacists recommended that all antibiotics should be discontinued and metronidazole and vancomycin be added. Antibacterial drugs and montmorillonite Sporadic interval of 2h taking, montmorillonite powder should be used to warm the water below 40 ℃ to take; to inform patients with oral vancomycin no effect on renal function; control of infection with macrolides or aminoglycosides. Results Physicians and patients adopted the recommendations of clinical pharmacists, after antibacterial drugs, probiotics, antidiarrheal agents in patients with defecation, body temperature, blood routine returned to normal. Conclusion The effective intervention and pharmacological nursing of clinical pharmacists are of great significance for the prevention and treatment of pseudomembranous colitis.