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氨基糖苷类抗生素与其他抗生素间的相互作用氨基糖苷类+两性霉素4例归因于艮他霉素和两性霉素联合应用而引起肾毒性的病例,其相互作用、机制、重要性和处理:4个病人应用中等剂量的艮他霉素和两性霉素 B 治疗,呈现出归因于两种药物合并使用的肾损害。已知这两种抗生素在足够高的剂量时都有肾毒性,而各自的低剂量合用,其肾毒性呈相加作用。如合用这两种抗生素,在没有更多的了解之前,必须仔细、慎重地检查肾功能。
Interactions between aminoglycoside antibiotics and other antibiotics Four cases of aminoglycosides plus amphotericin due to nephrotoxicity due to combination of gentamycin and amphotericin, their interaction, mechanism, importance, and management : Four patients treated with medium dose gentamicin and amphotericin B showed renal impairment due to combined use of the two drugs. Both antibiotics are known to be nephrotoxic at sufficiently high doses, and their respective nephrotoxic effects are additive at their respective lower doses. As with these two antibiotics, you need to carefully and carefully check your kidney function before you learn more about it.