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目的 在 6个月固定化疗期全程每日给药化疗方案的基础上 ,观察进一步缩短化疗期的远期疗效。方法 采用 2HRZS(E) /XH3 R3 化疗方案治疗初治涂阳肺结核 ,经涂片检查痰菌阴转后连续3个月阴性为治疗停药标准 ,并注意抓好研究过程中的环节质量控制。结果 符合选例标准 95例 ,92例完成规则治疗 ,累计痰菌阴转率为 98.9% ,91例治愈 ,平均化疗期为 5 .1个月 ,2年随访率为 91 .2 % ,细菌学复发率为 2 .3 %。结论 本研究与国内 6个月标准短化相比 ,其复发率相近。说明本方案治愈率高 ,可缩短治疗期
Objective To observe the long-term effects of chemotherapy during the 6-month fixed chemotherapy period on the basis of daily chemotherapy regimen. Methods The initial treatment of smear-positive pulmonary tuberculosis was treated with 2HRZS (E) / XH3 R3 chemotherapy. After 3 months of smear-negative sputum negative conversion, the standard for stopping treatment was negative. Pay attention to the quality control during the study. Results Ninety-five patients were selected according to the selection criteria. 92 patients underwent regular treatment. The cumulative sputum negative conversion rate was 98.9%, 91 patients were cured, the average chemotherapy period was 5.1 months, and the 2-year follow-up rate was 91.2%. Bacteriological The recurrence rate was 2.3%. Conclusion This study compared with the standard shortening of 6 months in China, the relapse rate was similar. This program shows a high cure rate, can shorten the treatment period