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目的:分析总结使用左氧氟沙星与阿奇霉素治疗慢性支气管炎的临床效果与安全性。方法:对110例慢性支气管炎患者的临床资料进行回顾分析,分为观察组与对照组各55例,观察组口服阿奇霉素,对照组口服左氧氟沙星,对比两组患者的临床效果及安全性。结果:治疗后第10d与第24d两组患者的临床疗效无明显差异(p>0.05),此外两组患者的肺功能改善程度与症状缓解情况也无明显差异(p>0.05)。在用药安全性上,两组患者均未出现明显不良反应,安全可靠。结论:治疗慢性支气管炎时,应用左氧氟沙星与阿奇霉素的临床效果均比较理想且接近,安全可靠,值得临床推广。
Objective: To analyze and summarize the clinical efficacy and safety of levofloxacin and azithromycin in the treatment of chronic bronchitis. Methods: The clinical data of 110 patients with chronic bronchitis were retrospectively analyzed. They were divided into observation group and control group, 55 cases each. The observation group received azithromycin orally and the control group received levofloxacin. The clinical efficacy and safety of the two groups were compared. Results: There was no significant difference in the clinical efficacy between the two groups on the 10th and 24th days (p> 0.05). In addition, there was no significant difference between the two groups in the improvement of pulmonary function and the relief of symptoms (p> 0.05). In medication safety, two groups of patients did not appear obvious adverse reactions, safe and reliable. Conclusion: In the treatment of chronic bronchitis, the clinical effects of levofloxacin and azithromycin are both ideal and close, safe and reliable, and worthy of clinical promotion.