患儿男,1(6/12)岁,生后6个月始反复发作的阵发性咳喘,吐白色粘液样痰,伴纳差、倦怠、吞咽困难、进行性消瘦。入院前二个月来较烦燥,四肢强直,头后仰,哭闹时上述症状加重,伴有全身不自主震颇,左腹部可扪及一包块。曾多次在外院就诊,疑为“肺炎”、病毒脑炎”、“免疫缺陷病”等,半月前又因发热、咳喘住院,患儿系第二胎第二产,足月顺产,父母非近亲结婚。体检:体格发育落后,智力低下,面色苍黄,头发稀疏,左眼裂小,集合性斜视, Children with male, 1 (6/12) years old, 6 months after onset of recurrent episodes of paroxysmal cough, spit white mucus-like sputum, with anorexia, fatigue, difficulty swallowing, progressive weight loss. Two months before admission more irritable, limbs stiff, head back, crying when the above symptoms worse, accompanied by involuntary shock, the left abdomen palpable mass. Has repeatedly visited the hospital, suspected “pneumonia”, viral encephalitis “,” immune deficiency disease "and so on, due to fever and cough and a half months ago, the hospital was second child secondary birth, term full-term, parents Non-relatives married. Physical examination: physical development, mental retardation, pale yellow, sparse hair, left eye crack small, set strabismus,