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[目的]探讨Barrett食管(BE)的临床特点及病因。[方法]对确诊的41例BE患者进行回顾性分析。[结果]41例BE患者表现为烧心、胸骨后疼痛、反酸等反流性食管炎症状及有反流性食管炎镜下表现者分别占75.61%、65.85%、58.54%和85.37%,伴胆汁反流者10例(24.40%),伴食管裂孔疝6例(14.63%),幽门螺杆菌(Hp)阳性者14例(34.15%)。[结论]BE多见于老年人,与胃食管反流密切相关,胆汁反流在BE的发病中可能占有重要地位,Hp感染与BE的确切关系有待进一步研究。
[Objective] To investigate the clinical features and etiology of Barrett’s esophagus (BE). [Methods] Forty-one patients with BE confirmed were retrospectively analyzed. [Results] 41 cases of BE patients showed 75.61%, 65.85%, 58.54% and 85.37%, respectively, with heartburn, retrosternal pain, reflux symptoms of reflux esophagitis and reflux esophagitis There were 10 cases (24.40%) with bile reflux, 6 cases (14.63%) with hiatal hernia and 14 cases (34.15%) with Helicobacter pylori (Hp) positive. [Conclusion] BE is more common in the elderly and is closely related to gastroesophageal reflux. Bile reflux may play an important role in the pathogenesis of BE. The exact relationship between Hp infection and BE remains to be further studied.