乳房早发育（ｐｒｅｍａｔｕｒｅｔｈｅｌａｒｃｈｅ，ＰＴ）是指女孩８岁前孤立性乳房发育，而无其它第二性征成熟体征出现，由Ｗｉｌｋｉｎｓ［１］首先提出。疾病好发年龄是自出生后至２岁时。此病属于性早熟的一种变异型，大多为良性自限性疾病，仅极少数会发展成中枢... Prematurethelarche (PT) refers to the development of isolated breasts in girls up to 8 years of age without other signs of secondary sexual maturity, first proposed by Wilkins [1]. Disease onset age is from birth to 2 years old. The disease is a variant of precocious puberty, mostly benign self-limiting disease, only a very few will develop into a central ...